Acarix

Bringing 21st century technology and mathematics together, the new CADScor® System signifies dramatic changes to advanced auscultation (listening to the internal sounds of the body).

The Acarix CADScor® System combines world class Danish acoustic knowledge and advanced algorithms into a new method for obtaining a patient specific CAD-score, for estimating the risk of suffering from coronary artery disease.

Coronary Artery Disease (CAD) is the most common heart disease affecting up to 50% of the westernized population during their lifetime. CAD is however not restricted to the industrialized world but also increasing dramatically in expanding economies like Brasilia, Russia, India, and China as well as in the developing world.

THE CHALLENGE

The value of persistent commitment is essential in medical device development. Glaze technical project management experience is essential to the success of Acarix.

The The Acarix CADScor® System project has been through all phases from the specification and architecture of the product through the MDD approval and all the way to maintenance, support and product updates and in that process Acarix has used technical expertise and management from Prevas, Kapacitet and Glaze.

One of the main challenges in the project has been to bring together the culture from a number of very different persons and companies. Mechanical Design, University Research, Production Facilities and Software Quality have all been coordinated in order to achieve the same goal - of getting the product to the market.

QUOTE

Claus BV Christensen, the COO at Acarix says: "We have enjoyed good overall budget adherence, expected technical expertise, and deadlines within agreed limits. The use of a dedicated project manager is an important asset for any project, to keep momentum, while the client is concentrating on other business. Keeping solid records (hours, budget, progression) and being able to analyze and communicate these important measures built transparency, trust and confidence. So I would recommend to keep that project structure for clients like Acarix, with limited electronic development resources and knowledge."

Positioning technologies currently applied across industries:

Global Navigational Satellite System: Outdoor positioning requires line-of-sight to satellites, e.g. GPS: the tracking device calculates its position from 4 satellites’ timing signals then transmits to receiving network
–    via local data network, e.g. wifi, proprietary Wide Area Network
–    via public/global data network, e.g. 3G/4G

Active RFID: A local wireless positioning infrastructure built on premises indoor or outdoor calculates the position based on Time of Flight from emitted signal & ID from the tracking device to at least 3 receivers or when passing through a portal. The network is operating in frequency areas such as 2.4 GHz WiFi, 868 MHz, 3.7 GHz (UWB – Ultra Wide Band), the former integrating with existing data network, the latter promising an impressive 0.3 m accuracy. Tracking devices are battery powered.

Passive RFID: Proximity tracking devices are passive tags detected and identified by a reader within close range. Example: Price tags with built-in RFID will set off an alarm if leaving the store. Numerous proprietary systems are on the market. NFC (Near Field Communications) signifies a system where the reader performs the identification by almost touching the tag.

Beacons: Bluetooth Low Energy (BLE) signals sent from a fixed position to a mobile device, which then roughly calculates its proximity based on the fading of the signal strength. For robotic vacuum cleaners an infrared light beacon can be used to guide the vehicle towards the charging station.

Dead Reckoning: Measure via incremental counting of driving wheels’ rotation and steering wheel’s angle. Small variations in sizes of wheel or slip of the surface may introduce an accumulated error, hence this method is often combined with other systems for obtaining an exact re-positioning reset.

Scan and draw map: Laser beam reflections are measured and used for calculating the perimeter of a room and objects. Used for instance when positioning fork-lifts in storage facilities.

Visual recognition: The most advanced degree of vision is required in fully autonomous vehicles using Laser/Radar (Lidar) for recognition of all kinds of object and obstructions. A much simpler method can be used for calculating a position indoor tracking printed 2D barcodes placed at regular intervals in a matrix across the ceiling. An upwards facing camera identifies each pattern and the skewed projection of the viewed angle.

Inertia: A relative movement detection likewise classical gyroscopes in aircrafts now miniaturised to be contained on a chip. From a known starting position and velocity this method measures acceleration as well as rotation in all 3 dimensions which describes any change in movement.

Magnetic field: a digital compass (on chip) can identify the orientation provided no other magnetic signals are causing distortion.

Mix and Improve: Multiple of the listed technologies supplement each other, well-proven or novel, each contributing to precision and robustness of the system. Set a fixpoint via portals or a visual reference to reset dead reckoning & relative movement; supplement satellite signal with known fixpoint: “real time kinematics” refines GPS accuracy to mere centimetres; combine Dead Reckoning and visual recognition of 2D barcodes in the ceiling.

LoRaWAN: A low power wide area network with wide reach. An open standard that runs at unlicensed frequencies, where you establish a network with gateways.

Sigfox: A low power wide area network reminiscent of LoRa. Offered in Denmark by IoT Danmark, which operates the nationwide network that integrates seamlessly to other national Sigfox networks in the world.

NFC: Used especially for wireless cash payments.

Zigbee: Used especially for home automation in smart homes, for example. lighting control.

NB-IoT: Telecommunications companies’ IoT standard. A low-frequency version of the LTE network.

2-3-4G Network: Millions of devices are connected to a small SIM card, which runs primarily over 2G, but also 3G and 4G.

Wifi: The most established standard, especially used for short-range networks, for example. in production facilities.

CATM1: A low power wide area network, especially used in the United States.